Reducing calorie intake may offer relief from fatigue in individuals battling multiple sclerosis (MS), according to recent research. The study, led by Professor Vijayshree Yadav at the Oregon Health & Science University, indicates a notable reduction in fatigue levels among MS patients who reduced their daily caloric intake by 19%. With no FDA-approved drug specifically for MS-related fatigue, these findings underscore the potential impact of dietary modifications on patients’ quality of life. The 16-week randomized trial involved 39 participants with MS and fatigue. One group followed a low-fat diet, while the control group maintained their regular diet. The study revealed a significant decrease in fatigue among those on the low-fat diet, emphasizing the potential role of nutrition in managing this debilitating symptom. Participants in the active group received nutrition counseling and adhered to a 12-week low-fat diet, monitored through routine blood sampling. Biomarkers confirmed adherence to the dietary regimen. Assessments included 24-hour diet recalls, a food frequency questionnaire, and the Modified Fatigue Impact Scale. These findings support earlier research suggesting the positive impact of low-fat diets on MS-related fatigue. While a 2016 study focused on plant-based diets, the recent research incorporated low-fat meat products, emphasizing the flexibility of dietary approaches. Notably, the study contrasts with the potential long-term drawbacks of high-fat diets, which have been linked to increased caloric consumption and weight gain. The research highlights the importance of individualized dietary interventions in managing symptoms and improving the overall well-being of MS patients.
Source: https://journals.sagepub.com/doi/10.1177/13524585231208330
