Omega-3 polyunsaturated fatty acids (PUFAs), particularly EPA, are emerging as powerful allies in slowing down the aging process. These essential fats help maintain energy metabolism by boosting fatty acid β-oxidation and ATP production in aging organs, reducing lipid accumulation and promoting lipid balance. As natural agonists of peroxisome proliferator-activated receptor α (PPARα), Omega-3 PUFAs enhance cellular function, prevent age-related damage, and support overall organ health. Supplementing with Omega-3s or using transgenic approaches that increase their levels can significantly slow the aging process, offering a promising strategy for healthy aging and longevity.
Source: https://www.sciencedirect.com/science/article/pii/S1043661824003293?via%3Dihub
