The study examines the impact of purple corn anthocyanins (APM) on obesity and metabolic health through hepatic AMP-activated protein kinase (AMPK) activation. Anthocyanins from purple corn (APM) supplementation at a dose of 400 mg per kilogram of body weight significantly reduced body weight, epididymal fat mass, total cholesterol, and triglyceride levels in high-fat diet (HFD)-induced obese mice. Additionally, it enhanced fat oxidation, inhibited lipid synthesis, and modulated gut microbiota composition by increasing the population of beneficial Lactobacillus bacteria while reducing the presence of harmful Helicobacter species. These findings suggest that purple corn anthocyanins could serve as a natural functional ingredient for obesity management and metabolic health support.
Source: https://www.sciencedirect.com/science/article/pii/S1756464621002310
