A recent study found that ꞵ-hydroxy-ꞵ-methylbutyrate (HMB) when combined with vitamin D, showed significant improvements in the ratio between the body’s muscle and fat content. The results of the study were published in the journal, Nutrients.
The study was conducted in a group of 43 middle-aged women and the results were studied after 12 weeks of supplementation. The participants were randomized into four-arm groups to receive either a combination of HMB and vitamin D or a placebo. These groups were further segregated into subgroups based on a progressive resistance exercise training program and a non-exercise sedentary control.
The results were analyzed using Magnetic Resonance Imaging (MRI) which found changes in lean muscle mass. Significant reductions were also seen in intermuscular adipose tissue (IMAT). Vitamin D levels were noted at baseline and at frequent intervals. Participants were found to have a vitamin D deficiency at baseline, and later, the concentrations increased between 8 and 12 weeks.
It was concluded that a combination of HMB and vitamin D supplementation may be associated with maintaining muscle size in non-exercise sedentary women.
Source: HMB and vitamin D supplementation linked to reduction in fat stores. Nutraceuticals World. 28 February, 2023.