A recent study revealed potential cognitive benefits of a lion’s mane mushroom extract, specifically SO-DSX1 from Sempera Organics, in young, healthy individuals. In a pilot study involving 41 adults aged 18-45, those receiving a daily 1.8-gram dose demonstrated enhanced performance on a Stroop task one hour post-supplementation. After 28 days, a trend toward reduced subjective stress was observed. While caution is urged in concluding cognitive improvement, it marks the first study highlighting cognitive benefits in young, healthy subjects. The extract, potentially influencing brain-derived neurotrophic factor (BDNF), may find application in cognitive performance supplements for younger adults seeking mental enhancement in work, career, or gaming.