Myo-Inositol Fails to Reduce Pregnancy Complications in PCOS Patients

Pregnant individuals living with polycystic ovary syndrome (PCOS) face an elevated risk of severe pregnancy complications, including gestational diabetes, preeclampsia, and preterm birth. To see if a popular dietary supplement could lower these risks, researchers conducted a rigorous, placebo-controlled clinical trial testing daily myo-inositol supplementation started early in pregnancy.
Despite widespread interest in its potential protective benefits, the study found that taking myo-inositol daily provided no significant reduction in pregnancy complications compared to a standard folic acid placebo. The rates of gestational diabetes, preeclampsia, and early delivery remained virtually identical between both groups, suggesting that myo-inositol is not an effective preventive treatment for high-risk pregnancies associated with PCOS.

Source : https://pmc.ncbi.nlm.nih.gov/articles/PMC12418221/