The clinical study assessed 500 mg/day of bitter hop extract (BHE) in adults with overweight or obesity following diet and exercise advice. BHE, rich in hop bitter acids, was designed to stimulate gut bitter taste receptors and promote the release of appetite-regulating hormones such as GLP-1, CCK, and PYY. Compared with placebo, BHE produced greater reductions in body weight and fat mass, with participants losing 3.8 kg (4.3%) of body weight and 4.5 kg of fat mass, compared with 0.4 kg and 0.7 kg, respectively in the placebo group. Visceral fat was also reduced, while skeletal muscle mass was maintained, with a small increase of 0.92 kg versus 0.23 kg in the placebo group. Participants also reported reduced hunger and food cravings. Bitter hop extract can support fat loss while helping preserve muscle mass when combined with diet and exercise.
Source : https://www.sciencedirect.com/science/article/pii/S2667368126000550?via%3Dihub
