Researchers optimized a turmeric:Arabica coffee:chili extract (1:3:4) that showed stronger antioxidant activity and comparable anti-inflammatory effects at lower, less cytotoxic doses.
The blend was loaded into nanostructured lipid carriers (spray-dried powder redispersing from ~258 nm to ~350 nm) with stable curcumin and capsaicin, suggesting a promising, stable low-dose supplement for reducing oxidative stress and inflammation.