Nettle Root Extract Blocks Hormone Carrier

Stinging nettle (Urtica dioica) root is used for benign prostatic hyperplasia. Researchers tested four nettle substances for effects on sex hormone–binding globulin (SHBG) binding to prostate membranes. Only the aqueous extract inhibited SHBG binding, starting at ~0.6 mg/ml and fully blocking it at 10 mg/ml, suggesting a water-soluble compound may underlie nettle’s prostate effects.

Source : https://pubmed.ncbi.nlm.nih.gov/7700987/