Synbiotic EDC‑HHA01: A Microbiome-Targeted Approach to Diabetes

The clinical study evaluating the impact of a microbiome‑targeted synbiotic formulation (EDC‑HHA01) in adults with prediabetes or Type 2 Diabetes Mellitus (T2DM). The intervention aimed to improve metabolic outcomes by combining prebiotic and probiotic components designed to influence gut microbial composition and function. Participants receiving EDC‑HHA01 were assessed for changes in insulin sensitivity, glycemic markers, systemic inflammation, and gut microbiota profiles over the study period. The results indicate that the synbiotic was well tolerated and safe, and was associated with improvements in metabolic parameters, including better glycemic control and reduced inflammatory markers, along with beneficial shifts in gut bacterial populations linked to metabolic health.

Source : https://www.mdpi.com/2076-2607/14/4/749