Curcuma aromatica based Hydrogel Patch: A Natural Approach for Acne and Skin Inflammation

The study focuses on developing a hydrogel patch using Curcuma aromatica extract to treat acne and skin inflammation. The patch was made with carrageenan, locust bean gum, PVP-K30, and glycerin, and contained 1% of the extract rich in curcumin. The formulation (CA2) showed good flexibility, smooth texture, and a skin-friendly pH around 5.5. It released about 19% of the extract within 30 minutes and around 50% after 12 hours, with 38% absorption through the skin in 24 hours. Tests showed that it reduced inflammation in macrophage cells and effectively inhibited Cutibacterium acnes, the bacteria responsible for acne. Analysis confirmed that even distribution of the extract in the hydrogel and its stability. Overall, the Curcuma aromatica hydrogel patch showed strong anti-inflammatory and anti-acne potential, suggesting it could be useful for cosmetic and dermatological applications.

Source : https://www.mdpi.com/2079-9284/12/6/240