Brain Training and Sulforaphane Independently Enhance Cognition, Without Additive Effects When Combined

In a 12-week double-blind randomized controlled trial involving 144 healthy older adults, brain training and sulforaphane supplementation each independently improved cognitive performance, but their combination did not yield additional benefits. Brain training using the Brain Age game significantly enhanced processing speed compared with an active control game, while sulforaphane intake improved both processing speed and working memory relative to placebo, regardless of game type. However, participants receiving both brain training and sulforaphane showed no greater cognitive gains than those receiving either intervention alone, suggesting overlapping or non-additive mechanisms underlying their effects on cognition.

Source : https://www.mdpi.com/2072-6643/13/2/352