A Botanical Breakthrough Redefines NAD⁺ Support for healthy ageing

A newly published clinical trial is set to reshape how the nutraceutical industry approaches NAD⁺ enhancement. In a peer-reviewed, randomized, double-blind, placebo-controlled study in the Journal of Functional Foods, researchers showed that the botanical complex BluNADBooster outperformed the long-standing benchmark NAD⁺ precursor, nicotinamide riboside (NR), across multiple healthy-ageing domains.The study demonstrated that BluNADBooster significantly improved biomarkers of mitochondrial health, energy metabolism, inflammation, cognition, physical performance, and quality of life. Notably, BluNADBooster increased blood NAD⁺ levels by 26.48%, surpassing NR alone, while the combination of BluNADBooster and NR achieved the greatest rise (31.76%). Unlike precursor-only strategies, BluNADBooster also modulated CD38 activity—an age-related driver of NAD⁺ decline—while delivering polyphenol-driven anti-inflammatory and cognitive benefits. These findings position BluNADBooster as a next-generation, plant-based approach to cellular energy, longevity, and proactive healthy ageing.

Source : Comparative efficacy of a standardized herbal composition LN22199, nicotinamide riboside, and their combination on NAD+ metabolism in healthy aging adults – ScienceDirect