Pycnogenol®: A Proven Powerhouse from French Maritime Pine Bark

Pycnogenol®, a patented extract from Pinus pinaster Ait. ssp. Atlantica bark, shines in 39 randomized, double-blind, placebo-controlled trials with over 2,000 participants. Supplementation (2 weeks to 6 months) delivers wide-ranging benefits: bolstering cardiovascular and endothelial health, easing chronic venous insufficiency, enhancing cognition, joint and skin elasticity, eye and women’s health, respiratory function, allergy relief, oral wellness, and sports performance.
Its power stems from potent antioxidative and anti-inflammatory actions, plus reinforcement of the extracellular matrix as shown in vitro, in vivo, and human studies. This review spotlights “gold standard” trial data across health domains, unpacks underlying mechanisms, and sets the stage for future research into this versatile extract

Source : https://pmc.ncbi.nlm.nih.gov/articles/PMC11096518/