In this 8-week study on women aged 30–50, a supplement with cherry blossom (sakura) and Rosa roxburghii fruit extract improved several signs of skin aging compared to placebo. It increased skin hydration, brightness, elasticity, and collagen index, while reducing roughness, scaliness, and wrinkles—including forehead lines, crow’s feet, and neck lines. The supplement was safe and showed clear anti-aging skin benefits.